What "evidence grades" mean β how to read π’π‘π
A common mistake when reading supplement information is treating it as "works" vs "doesn't work." Real scientific evidence varies in strength by context. GOT JI EUN labels every ingredient with a three-tier evidence grade.
π’ Strong
Consistent effects across multiple large randomized controlled trials (RCTs) and meta-analyses β typically when correcting a deficiency. Supplementing a vitamin-D-deficient person clearly benefits bone health.
π‘ Moderate
Some trials show benefit, but results are mixed or limited to certain groups. Omega-3 strongly lowers triglycerides, yet large trials (VITAL) did not clearly show cardiovascular prevention in people who are not deficient.
π Limited / mixed
Mostly small or observational studies, or inconsistent large trials. This does not mean "no effect" β it means "evidence is still building." Silymarin from milk thistle has established antioxidant properties in vitro, but human clinical liver-protection data are still emerging.
Key: separate "correcting deficiency" from "general prevention"
Filling a gap in someone who is deficient is a different question from preventing disease in someone already replete. We always separate the two. The most evidence-based first step is asking "Am I actually low in this?"
Sources: NIH ODS, Cochrane Reviews, Manson JE et al. VITAL (NEJM 2019).